• PERSONALIZED MEDICINE IN INFECTIONS DISEASES

  • PERSONALIZED MEDICINE IN INFECTIONS DISEASES

PerAID

The PerAID project proposes to boost personalized medicine (PM) in severe infectious diseases, specifically focusing on the life-threatening necrotizing soft tissue infections (NSTI) as well as the large heterogeneous group of sepsis patients. Personalized medicine is a neglected, albeit much desired, development in the field of acute infectious diseases.

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PerMIT

PerMIT is supported by the ERAPerMed initative for joint transnational projects on Personalized Medicine  – smart combination of pre-clinical and clinical research with data and ICT solutions. To achieve its objective, the project builds on a transnational interdisciplinary team of clinicians, experimentalists, bioinformaticians and computational modellers.

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INFECT

The INFECT-project included 14 multidisciplinary partners from across Europe, Israel and the US.

The overall goal of the project was to advance our understanding of the pathophysiological mechanisms, prognosis, and diagnosis of the multifactorial highly lethal necrotizing soft tissue infections (NSTIs).

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THE PUBLIC

Despite access to modern intensive care and antibiotics, acute bacterial infections, such as severe sepsis and deep tissue infections are life-threatening conditions affecting several millions of persons worldwide.

Skin and soft tissue infections are common and range in severity from superficial uncomplicated infections to life-threatening deep tissue infections, which spread rapidly and often require extensive surgery, sometimes even amputation.

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HEALTH CARE & RESEARCHERS

Severe acute infectious diseases, such as deep tissue infections and sepsis, are complex multifactorial diseases that can be caused by a variety of microbes. They are frequently complicated by septic shock and multi-organ failure.

Despite modern medicine, the mortality is high, often exceeding 25%, and in the severe deep tissue infections, amputation is required in up to 15% of the cases.

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PARTNERS & NATIONAL FUNDING AGENCIES